Karen Ann Derepkowski (nee Rottler) of Germantown, WI passed away peacefully at the age of 72 on Sunday, May 9th, 2021 at Lawlis Hospice. She was born on October 7th, 1948 to Herbert and Jeanette (nee Klapperich) Rottler in Milwaukee, WI. She was a graduate of St. John's Cathedral High School in 1966. She is survived by her husband, Arthur Derepkowski and her daughter, Deborah (Jason) Hamilton. She was the loving grandmother of Abigail and Riley Hamilton. She is further survived by her brother, Ronald (Gayle) Rottler and nieces, Cathie (Joe) Petoskey, Sandy (Chad) Berge and Beth (Anthony) Plageman, brother-in-law, David Derepkowski (late Terri Derepkowski), and great nieces, great nephew, cousins, family and many friends (including the "PIGS"). A funeral mass will be celebrated on Friday, May 21, 2021 at 6:30pm, St. Boniface Catholic Church, W204 N11940 Goldendale Rd. Germantown, WI 53022. Karen's family will greet family and friends beginning at 5:30. St. Boniface asked that all visitors wear a mask while inside.